In Asia, where the use of inovapure in over-the-counter products is very common, different products include the treatment of colds, infection, sore throats, sinusitis and athlete’s foot.

In the European market, inovapure is marketed as an effective component in throat lozenges. In the United States, this enzyme is used in a range of mouth care products (toothpaste, mouthwash and oral gel) designed for people with dry mouth (Xerostomia). Diseases ranging from diabetes to Sjogren’s disease to AIDS can cause dry mouth; it also occurs in people undergoing radiation treatment or taking certain prescription medications.

Considerable research has been done over the past thirty years to identify specific pharmaceutical applications. Potential applications include treatment of topical bacteria and fungi, problematic oral flora, and even viruses. Efficacy has been demonstrated in several areas, and potential uses for this naturally occurring enzyme have been identified through scientific research, including:

• inhibition of the influenza virus;
• inhibition of streptococcus spp and other bacteria commonly associated with throat infections;
• treatment of herpes viruses, including Herpes simplex and Herpes zoster;
• controlling the propagation of the AIDS virus, when combined with another naturally occurring human enzyme, deoxyribonuclease;
• preventing alveolar pyorrhea and gingivitis with a dental cream; and
• treatment of wounds, burns and athlete’s foot.