Neova’s specialty proteins can be used in numerous applications including immunodiagnostics, protein purification and cell biology/cell culture. These specialty proteins are of extremely high purity and can be customized to meet the end user’s specific needs.

Immunodiagnostics
Avidin is a glycoprotein with a strong affinity for binding biotin (vitamin H). This unique characteristic has given rise to biotin–avidin technology in applications including affinity chromatography, immunohistochemistry (using biotinylated probes), immunoassays and diagnostics.

Cell Biology / Cell Culture
Since ovalbumin is very similar in structure to Bovine Serum Albumin (BSA), it may be used as a substitute in many applications.

Ovotransferrin is very similar to both human and bovine derived transferrins, including lactoferrin, and can serve as a substitute in most instances. Transferrins have been identified as a required media ingredient for the maturation of cells as they play a key role in providing iron for cell growth. They also detoxify the media by binding contaminating metal ions.

Ovomucoid is a natural trypsin inhibitor, making it an excellent replacement for serum trypsin inhibitor in tissue culture research.

Protein Purification / Chemistry
Both avidin and ovotransferrin are available in high purity, which makes them appropriate in the production of polyclonal antibodies. Avidin can also be used in standards and models in molecular weight determination, while ovotransferrin can be used in structural elucidation studies.

Being a natural inhibitor of trypsin, purified ovomucoid can be used as a ligand in affinity purification of porcine and bovine trypsin following immobilization onto a suitable matrix.